E3 ligase and a very selective kinase inhibitor for a BMP-type I receptor, both currently undergoing clinical evaluation. From 2013 to 2023 she was the director of the Joint, Bone and Tendon Research Unit of MSD and since 2023 she leads the in vitro Discovery Unit of “Disease of Aging and Regenerative Medicine” in Biomedical Research, Novartis, Basel.
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Dive into the critical stages of drug development with our Lead Selection & Optimization course. Learn to identify potential leads, understand their characteristics, and optimize them for clinical use through a real-world case study on antimalarial therapy.
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Embark on a journey into the world of drug development with our Targets, Assays & Screening course. Delve into the critical initial phases where potential drugs are identified from vast libraries of molecules. This course will equip you with an understanding of various assays and screening methods used to pinpoint compounds that could lead to breakthrough therapies.
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Embark on a journey into the world of Pharmacokinetics with this engaging online course offered by Coursera. Designed for students and professionals alike, this course provides an in-depth understanding of critical concepts such as absorption, distribution, metabolism, excretion (ADME), and how to interpret drug concentration-time data to calculate essential pharmacokinetic parameters like volume of distribution, half-life, and clearance.
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Explore the critical role of patient safety in drug discovery with our Preclinical Safety course on Coursera. Delve into the lessons learned that shape current safety evaluations, understand the purpose and methods behind toxicology and safety studies, and learn how to assess and mitigate risks for new medications.
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Embark on a comprehensive journey through pre-formulation with this Coursera course. Master the art of developing active compounds into effective formulations for animal studies and early human clinical trials. Explore critical aspects like enhancing drug solubility, selecting the right crystalline form, determining the route of administration, and understanding the nuances between drug substance and drug product.
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Dive into the world of pharmacology with our 'Introduction to Drug Hunting' course. This beginner-friendly program offers a high-level overview of the critical steps in preclinical drug discovery, including research, development, and the crucial role of competitive intelligence in project strategy. Ideal for those new to the field or seeking a broad understanding before delving deeper.