NAU

Introdução à Epigenética (NAU)

Introdução à Epigenética (NAU)

O curso “Introdução à Epigenética” tem como principal finalidade conhecer as principais marcas epigenéticas e sua associação á remodelação da cromatina e controlo da expressão génica".

Os mecanismos epigenéticos encontram-se intimamente relacionados com a problemática do cancro uma vez que, apesar de se reconhecer o papel fundamental da perda de genes supressores de tumores (mutações ou deleções), a metilação de DNA constitui também um mecanismo vital no silenciamento de genes críticos na carcinogénese. A identificação e avaliação das marcas epigenéticas fornecem informações importantes para o diagnóstico e prognóstico de patologias como o cancro.

O extraordinário potencial e aplicabilidade da epigenómica fomentam uma necessidade crescente de enquadrar esta área emergente da ciência no contexto do diagnóstico clínico, para a qual, atualmente, a oferta de ações formativas é ainda diminuta, sendo a presente MOOC uma oportunidade para se iniciar na epigenética: A MOOC terá como objetivos de formação:

  • Identificar as principais marcas epigenéticas;
  • Conhecer os principais mecanismos de regulação epigenética da expressão génica.

Informação sobre o curso
Formato: Curso de formação on-line, em formato MOOC (Massive Open Online Course)
Inscrição: Gratuita, sendo necessário o registo prévio na plataforma NAU
Âmbito: Ciências da Vida; Ciências da Saúde
Iniciativa: Instituto Politécnico de Lisboa
Apoio Institucional: Escola Superior de Tecnologia da Saúde de Lisboa
Organização: Módulos com vídeos e legendados em português e questões interativas

Programa

Introdução
Módulo I: Epigenética: da história à atualidade
Módulo II: Epigenética: níveis e organização da cromatina
Módulo III: Epigenética: marcas epigenéticas e regulação da cromatina

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