In this course, you will follow in the footsteps of the bioinformaticians investigating the COVID-19 outbreak by annotating the SARS-CoV-2 genome and using the annotation to design a COVID-19 diagnostic test. Whether you’re new to the world of computational biology, or you’re a bioinformatics expert seeking to learn about its applications in the COVID-19 pandemic, or somewhere in between, this course is for you!
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As you go through this journey, we will introduce and explain genomic concepts and give you many opportunities to practice your skills, and we will provide a series of problems with gradually increasing complexity. This second course will only discuss the annotation of the SARS-CoV-2 genome, but future courses in this series will explore follow-up bioinformatics analyses used in the COVID-19 pandemic.
Syllabus
WEEK 1
In Chapter 3, we will explore how to use bioinformatics to aid in rapidly diagnosing patients who may be infected with COVID-19. Much like how laboratories around the world have been hard at work developing methods to test for COVID-19, we will now try to design our own diagnostic test.
WEEK 2
In Chapter 4, we will use the SARS-CoV-2 genome annotation to design our own COVID-19 diagnostic test and will learn how to measure its accuracy.
