Statistical Inference and Hypothesis Testing in Data Science Applications (Coursera)

Statistical Inference and Hypothesis Testing in Data Science Applications (Coursera)

This course will focus on theory and implementation of hypothesis testing, especially as it relates to applications in data science. Students will learn to use hypothesis tests to make informed decisions from data. Special attention will be given to the general logic of hypothesis testing, error and error rates, power, simulation, and the correct computation and interpretation of p-values. Attention will also be given to the misuse of testing concepts, especially p-values, and the ethical implications of such misuse.

Class Deals by MOOC List - Click here and see Coursera's Active Discounts, Deals, and Promo Codes.

This course can be taken for academic credit as part of CU Boulder’s Master of Science in Data Science (MS-DS) degree offered on the Coursera platform. The MS-DS is an interdisciplinary degree that brings together faculty from CU Boulder’s departments of Applied Mathematics, Computer Science, Information Science, and others. With performance-based admissions and no application process, the MS-DS is ideal for individuals with a broad range of undergraduate education and/or professional experience in computer science, information science, mathematics, and statistics.

What You Will Learn

  • Define a composite hypothesis and the level of significance for a test with a composite null hypothesis.
  • Define a test statistic, level of significance, and the rejection region for a hypothesis test. Give the form of a rejection region.
  • Perform tests concerning a true population variance.
  • Compute the sampling distributions for the sample mean and sample minimum of the exponential distribution.

Course 3 of 3 in the Data Science Foundations: Statistical Inference Specialization

Syllabus

WEEK 1
Fundamental Concepts of Hypothesis Testing
In this module, we will define a hypothesis test and develop the intuition behind designing a test. We will learn the language of hypothesis testing, which includes definitions of a null hypothesis, an alternative hypothesis, and the level of significance of a test. We will walk through a very simple test.

WEEK 2
Composite Tests, Power Functions, and P-Values
In this module, we will expand the lessons of Module 1 to composite hypotheses for both one and two-tailed tests. We will define the “power function” for a test and discuss its interpretation and how it can lead to the idea of a “uniformly most powerful” test. We will discuss and interpret “p-values” as an alternate approach to hypothesis testing.

WEEK 3
t-Tests and Two-Sample Tests
In this module, we will learn about the chi-squared and t distributions and their relationships to sampling distributions. We will learn to identify when hypothesis tests based on these distributions are appropriate. We will review the concept of sample variance and derive the “t-test”. Additionally, we will derive our first two-sample test and apply it to make some decisions about real data.

WEEK 4
Beyond Normality
In this module, we will consider some problems where the assumption of an underlying normal distribution is not appropriate and will expand our ability to construct hypothesis tests for this case. We will define the concept of a “uniformly most powerful” (UMP) test, whether or not such a test exists for specific problems, and we will revisit some of our earlier tests from Modules 1 and 2 through the UMP lens. We will also introduce the F-distribution and its role in testing whether or not two population variances are equal.

WEEK 5
Likelihood Ratio Tests and Chi-Squared Tests
In this module, we develop a formal approach to hypothesis testing, based on a “likelihood ratio” that can be more generally applied than any of the tests we have discussed so far. We will pay special attention to the large sample properties of the likelihood ratio, especially Wilks’ Theorem, that will allow us to come up with approximate (but easy) tests when we have a large sample size. We will close the course with two chi-squared tests that can be used to test whether the distributional assumptions we have been making throughout this course are valid.

Go to Class
MOOC List is learner-supported. When you buy through links on our site, we may earn an affiliate commission.

Related Courses

Principles of fMRI 1 (Coursera) Coursera
Johns Hopkins University

Principles of fMRI 1 (Coursera)

Functional Magnetic Resonance Imaging (fMRI) is the most widely used technique for investigating the living, functioning human brain as people perform tasks and experience mental states. It is a convergence point for multidisciplinary work from many disciplines. Psychologists, statisticians, physicists, computer scientists, neuroscientists, medical researchers, behavioral scientists, engineers, public health researchers, biologists, and others are coming together to advance our understanding of the human mind and brain. This course covers the design, acquisition, and analysis of Functional Magnetic Resonance Imaging (fMRI) data, including psychological inference, MR Physics, K Space, experimental design, pre-processing of fMRI data, as well as Generalized Linear Models (GLM’s).

Aug 17th 2026
4 Weeks
Introduction to Statistics (Coursera) Coursera
Stanford University

Introduction to Statistics (Coursera)

Stanford's "Introduction to Statistics" teaches you statistical thinking concepts that are essential for learning from data and communicating insights. By the end of the course, you will be able to perform exploratory data analysis, understand key principles of sampling, and select appropriate tests of significance for multiple contexts. You will gain the foundational skills that prepare you to pursue more advanced topics in statistical thinking and machine learning.

Aug 10th 2026
5-12 Weeks
Visualization for Data Journalism (Coursera) Coursera
University of Illinois at Urbana-Champaign

Visualization for Data Journalism (Coursera)

While telling stories with data has been part of the news practice since its earliest days, it is in the midst of a renaissance. Graphics desks which used to be deemed as “the art department,” a subfield outside the work of newsrooms, are becoming a core part of newsrooms’ operation. Those people (they often have various titles: data journalists, news artists, graphic reporters, developers, etc.) who design news graphics are expected to be full-fledged journalists and work closely with reporters and editors.

Aug 10th 2026
5-12 Weeks
Applied Plotting, Charting & Data Representation in Python (Coursera) Coursera
University of Michigan

Applied Plotting, Charting & Data Representation in Python (Coursera)

This course will introduce the learner to information visualization basics, with a focus on reporting and charting using the matplotlib library. The course will start with a design and information literacy perspective, touching on what makes a good and bad visualization, and what statistical measures translate into in terms of visualizations. The second week will focus on the technology used to make visualizations in python, matplotlib, and introduce users to best practices when creating basic charts and how to realize design decisions in the framework.

Aug 10th 2026
4 Weeks
Machine Learning Rapid Prototyping with IBM Watson Studio (Coursera) Coursera
IBM

Machine Learning Rapid Prototyping with IBM Watson Studio (Coursera)

An emerging trend in AI is the availability of technologies in which automation is used to select a best-fit model, perform feature engineering and improve model performance via hyperparameter optimization. This automation will provide rapid-prototyping of models and allow the Data Scientist to focus their efforts on applying domain knowledge to fine-tune models. This course will take the learner through the creation of an end-to-end automated pipeline built by Watson Studio’s AutoAI experiment tool, explaining the underlying technology at work as developed by IBM Research.

Aug 17th 2026
4 Weeks
Business Applications of Hypothesis Testing and Confidence Interval Estimation (Coursera) Coursera
Rice University

Business Applications of Hypothesis Testing and Confidence Interval Estimation (Coursera)

Confidence intervals and Hypothesis tests are very important tools in the Business Statistics toolbox. A mastery over these topics will help enhance your business decision making and allow you to understand and measure the extent of ‘risk’ or ‘uncertainty’ in various business processes. This course advances your knowledge about Business Statistics by introducing you to Confidence Intervals and Hypothesis Testing. These are done by easy to understand applications.

Aug 10th 2026
4 Weeks
Data Science in Health Technology Assessment (Coursera) Coursera
Genentech

Data Science in Health Technology Assessment (Coursera)

This course explores key concepts and methods in Health Economics and Health Technology Assessment (HTA) and is intended for learners who have a foundation in data science, clinical science, regulatory and are new to this field and would like to understand basic principles used by payers for their reimbursement decisions.

Aug 17th 2026
3 Weeks
Materials Data Sciences and Informatics (Coursera) Coursera
Georgia Institute of Technology

Materials Data Sciences and Informatics (Coursera)

This course aims to provide a succinct overview of the emerging discipline of Materials Informatics at the intersection of materials science, computational science, and information science. Attention is drawn to specific opportunities afforded by this new field in accelerating materials development and deployment efforts.

Aug 10th 2026
5-12 Weeks
Improving Your Statistical Questions (Coursera) Coursera
Eindhoven University of Technology

Improving Your Statistical Questions (Coursera)

This course aims to help you to ask better statistical questions when performing empirical research. We will discuss how to design informative studies, both when your predictions are correct, as when your predictions are wrong. We will question norms, and reflect on how we can improve research practices to ask more interesting questions.

Aug 10th 2026
5-12 Weeks