Understanding pharmacokinetics, from basic principles to clinical applications. Explore the key principles of pharmacokinetics and how to apply them. On this course you will learn about the principles of clinical pharmacokinetics, including factors that affect the absorption, distribution, metabolism, excretion, and binding of drugs.
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You will learn how to integrate these principles into the process of monitoring, evaluating and adjusting dosing for patients.
You will learn through critical thinking and problem-solving exercises that relate to drug dosing and monitoring functions, that are commonly performed by pharmacists in clinical practice.
What topics will you cover?
- The fish tank – A simplified model of first-order elimination
- Dosing basics – How to determine the right amount of drug for a patient
- The ups and downs of predicting changes in drug concentration
- The challenges of assessing renal and hepatic clearance
- What pharmacists need to know about dosing aminoglycosides and vancomycin
- Clinical application - vancomycin and gentamycin case practice
What will you achieve?
By the end of the course, you'll be able to...
- Identify factors that affect the absorption, distribution, metabolism, excretion, and binding of drugs
- Interpret laboratory results, assess clinical findings
- Apply pharmacokinetic concepts in order to determine an individualized dosage regimen for a specific patient
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